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From Mary Kugler, R.N., Former About.com Guide to Rare Diseases

Experimental treatment for mouse muscular dystrophy

Wednesday October 18, 2006
Lab mouseA study published September 17, 2006, online at Nature Medicine looked at the potential use of existing experimental drugs, called histone deacetylase inhibitors, in treating muscular dystrophy. The international research team discovered that treating mice with muscular dystrophy with one of the drugs, Trichostatin A, restored skeletal muscle mass and prevented impaired muscle function. The treated mice were able to perform physical exercise similar to disease-free mice, and under the microscope their muscle tissues looked normal. Future research will determine whether the use of histone deacetylase inhibitors will be an effective treatment for muscular dystrophy in humans.

Comments

October 22, 2006 at 7:58 pm
(1) Cynthia Mendez says:

Hi i just read the article of the experiment you are doing for people with muscular dystrphy i have a 4yrs old son with congential muscular dystophy and im interested in the experiment for him does he quailfy for it what steps do i have to take for it and where would the experiement would take place we live in new york city

October 24, 2006 at 8:46 pm
(2) Rare Diseases Guide says:

This study was done only using mice. If you would like to know about experiments in humans with muscular dystrophy, the National Institutes of Health has a list you can see.

December 17, 2007 at 5:16 am
(3) Aasheesh K Raman says:

hi i read this article but i want to know what are the side effect of this medicine on the human as well as pets.can u give me the details on my mail id ashishraman19@rediffmail.com

im waiting for your response.

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