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By Mary Kugler, R.N., About.com Guide to Rare Diseases since 2000

More PANDAS evidence

Tuesday July 19, 2005
Dr. Robert L. Davis from Group Health Cooperative in Seattle, Washington, and his colleagues wanted to examine the relationship between group A beta-hemolytic streptococcal infection and the onset of obsessive-compulsive disorder (OCD), Tourette syndrome, and tic disorder, an autoimmune syndrome known as PANDAS. They matched 144 children between the ages of 4 and 13 who received a first diagnosis of one of the PANDAS disorders over an 8-year period with healthy children. According to the results published in the July, 2005, issue of Pediatrics, streptococcal infection seemed to double the risk for a first diagnosis of OCD, Tourette's, or tic disorder within the first 3 months after infection. Multiple infections seemd to triple the risk for a first diagnosis within 12 months. The researchers suggest that more needs to be discovered about which children are at greatest risk for developing PANDAS.

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